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Index > Protein center > TNFRSF18(Gene name) > Human
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  • TNFRSF18 (Gene name),
  • Tumor necrosis factor receptor superfamily member 18 (Protein name ),  TNR18_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFRSF18(UNQ319/PRO364;AITR;GITR);
    Protein name:
    Tumor necrosis factor receptor superfamily member 18;
    Alternative:
    Glucocorticoid-induced TNFR-related protein;Activation-inducible TNFR family receptor;
    CD:
    CD357;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6. Binds through its C-terminus to SIVA1/SIVA.
    Function:
    Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    241
    Sequence:
    50:
    MAQHGAMGAF | RALCGLALLC | ALSLGQRPTG | GPGCGPGRLL | LGTGTDARCC | 
    100:
    RVHTTRCCRD | YPGEECCSEW | DCMCVQPEFH | CGDPCCTTCR | HHPCPPGQGV | 
    150:
    QSQGKFSFGF | QCIDCASGTF | SGGHEGHCKP | WTDCTQFGFL | TVFPGNKTHN | 
    200:
    AVCVPGSPPA | EPLGWLTVVL | LAVAACVLLL | TSAQLGLHIW | QLRSQCMWPR | 
    241:
    ETQLLLEVPP | STEDARSCQF | PEEERGERSA | EEKGRLGDLW | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    E9333m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    E9333h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    U9333m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    U9333h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    P9333Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 18
    Cat.:
    P9333Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 18
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 18
    Protein for Human Tumor necrosis factor receptor superfamily member 18
    Protein for Human Tumor necrosis factor receptor superfamily member 18

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    Linearity
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    References
    1. 1.
      "Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR."
      Gurney A.L. , Marsters S.A. , Huang R.M. , Pitti R.M. , Mark D.T. , Baldwin D.T. , Gray A.M. , Dowd A.D. , Brush A.D. , Heldens A.D. , Schow A.D. , Goddard A.D. , Wood W.I. , Baker K.P. , Godowski P.J. , Ashkenazi A.
      Curr. Biol.9:215-218(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH TRAF1; TRAF2 AND TRAF3
      tissue: Bone marrow.
    2. 2.
      "Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand."
      Kwon B. , Yu K.-Y. , Ni J. , Yu G.-L. , Jang I.-K. , Kim Y.-J. , Xing L. , Liu D. , Wang S.-X. , Kwon B.S.
      J. Biol. Chem.274:6056-6061(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: T-cell.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Thymus.
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    9. 9.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-40
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